Skin cancer most often develops on areas of your body that get the greatest exposure to the suns ultraviolet (uv) rays. Skin cancer that occurs in the facial area should be treated immediately to prevent further spread of disease and the possibility of scarring 2. There are two main types of skin cancers, melanoma and keratinocyte. Melanomas are derived from melanocytes that create the pigment. In recent years, skin cancer experts have developed guidelines for when its best to use this technique based on the type and size of skin cancer, where it is on the body, and other important features. If lymph nodes near a squamous or basal cell skin cancer are enlarged,. facial swelling has a range of possible causes, from minor events like sleeping on your face to serious medical conditions like anaphylaxis. Melanoma, the most dangerous type of skin cancer, may appear as a change in an existing mole a small, dark, multicolored spot with irregular borders -- either elevated or flat -- that may bleed. , affects a growing number of people each year, raising public awareness and concern as we seek better ways to both prevent and treat the disease. , over three million people receive a non-melanoma skin cancer diagnosis each year, with rates of malignant melanoma, one of the most serious forms of the disease, rising. Skin that may look like an orange peel (swollen with small indentations) small blisters that leak clear fluid. Edema is a condition in which fluid builds up in your bodys tissues. The swelling may be caused by chemotherapy, cancer, and conditions not related to cancer. Learn about signs of edema, including swelling in your feet, ankles, and legs.