You might be surprised to learn that the sexually transmitted human papilloma virus (hpv) is a leading cause of throat cancers, and it. oral sex does not directly cause throat cancer, but it can spread hpv. Theres very little research thats looked at the possible risks from giving oral sex to a man compared with giving oral sex to a woman. But we do know that hpv-related oropharyngeal cancer (the part of the throat directly behind the mouth) is twice as common in men than women, and is most common in heterosexual men in their 40s and 50s. For men, the risk of hpv-driven cancers of the head and neck rise along with the number of oral sex. increasing rates of hpv infection, spread through oral sex, is largely driving the rapid rise in oropharyngeal cancers, which include tumors of the throat, tonsils, and base of the tongue, said. Yes, you can get throat cancer from oral sex, says american cancer society chief medical officer otis brawley, md. Its not oral sex, per se, that causes cancer, but the human papillomavirus (hpv.). on sunday, in an interview with the guardian, actor michael douglas revealed that his throat cancer was not caused by tobacco and alcohol, but by hpv, which was transmitted through oral sex. He has since called the statement a misunderstanding, but its still true you can get throat cancer from hpv. In an eye-poppingly candid interview with the guardians xan brooks, douglas, who is. how is oral sex linked to throat cancer? About 70 percent of oropharyngeal cancers are caused by hpv, says the national cancer institute. actor michael douglas, 75, infamously blamed his throat cancer diagnosis on his fondness for oral sex. it is transmitted to the mouth and throat mostly by performing oral sex and appears to cause about 70 percent of oropharyngeal cancers.